Table of Contents
The key difference between flocculation and deflocculation is that flocculation is the formation of flocs by the clumping of fine particles, whereas deflocculation is the dispersion of flocs to form a stable colloid. Flocculation refers to the formation of clumps from fine particles in a colloid.
What is meant by Deflocculation?
: to reduce or break up from a flocculent state : convert into very fine particles : disperse or maintain in a dispersed state.
What are the differences between flocculated and non flocculated suspension?
The suspension are said to be flocculated ,when the individual particles are in contact with each other and form a network like structure . Whereas in case of non-flocculated suspensions,the individual particles exists as a separate entity. In Non-flocculated suspensions The rate of sedimentation is slow.
How will you maintain stability of suspension?
Particle radius (a) will have a large bearing on suspension stability. To maintain stability through Brownian motion we need to prevent particles sticking when they collide. This can be achieved by increasing the charge associated with the particle i.e. zeta potential.
Is darvan a flocculant?
In ceramics, there are a number of different deflocculants available. Darvan is a liquid deflocculant that is often preferred for use with plaster molds because, unlike some other deflocculants, Darvan does not degrade the plaster.
Why does my clay smell?
When clay is stinky, though, it’s usually good, since that smell only comes when the clay has spent some time in the wet condition. If your clay stinks, that’s a good thing. It means there’s bacteria in it, living on the organic matter in it.
How can flocculation be prevented?
When particles of a suspension come close together they can form aggregates called flocculates which will settle more rapidly. To prevent that we often coat the particle with a charged surfactant. The charge (Zeta potential) acts to keep the particles separate and prevent flocculation.
Is Magma a coarse dispersion?
Dispersions containing particles of smaller size are termed fine dispersions (0.5 to 10 μm) colloidal range, Magmas and gels are fine dispersions .
What sedimentation means?
Sedimentation is the tendency for particles in suspension to settle out of the fluid in which they are entrained and come to rest against a barrier. Settling is the falling of suspended particles through the liquid, whereas sedimentation is the termination of the settling process.
How does particle size affect stability of suspension?
In terms of stability, particle size has a direct effect on the ease of maintenance of a uniform suspended phase. However, for larger particles, the effect of gravity becomes significant, especially if there is a sizeable difference in density between the dispersed and continuous phases.
Why are suspending agents used?
2. SUSPENDING AGENTS Suspending agents also called thickening agents are used to stabilize suspensions are hydrophilic colloid i.e. substances that spontaneously form colloidal dispersions with water because of an affinity between the dispersed particles and the dispersion medium.
What is flocculation degree?
Flocculation is defined as the process by which fine particles, suspended in a liquid medium, form stable aggregates called flocs. The degree of flocculation can be defined mathematically as the number of particles in a system before floc- culation divided by the number of particles (flocs) after flocculation.
Which agents are used for stability of suspension?
Xanthan gum in drug delivery applications XG is widely used as a suspending agent and stabilizer in suspension due to its safety properties in food and drug applications. Moreover, it is soluble in water and can provide sufficient viscosity in low concentration.
Why suspension is formulated?
Suspension can improve chemical stability of certain drug. For example Procaine penicillin G. Drug in suspension exhibits higher rate of bioavailability than other dosage forms.
Why do Flocculated particles not cake?
Repulsive forces between particles are overcome and a hard cake is formed which is difficult, if not impossible, to redisperse. The sediment is loosely packed and possesses a scaffold-like structure (large volume of final sediment). Particles do not bond tightly to each other and a hard, dense cake does not form.
Which suspension is more stable and why?
Suspension is more stable. This is because suspension does not mix with each other. The denser particles settle down at the bottom and makes the solution stable.
What’s the definition of bioavailability?
Bioavailability refers to the extent a substance or drug becomes completely available to its intended biological destination(s).
Is Redisperse difficult?
The repulsive forces between individual particles allow them to slip past each other as they sediment. The slow rate of settling prevents the entrapment of liquid within the sediment, which thus becomes compacted and can be very difficult to redisperse.
What is the other name of Deflocculation?
What is another word for Deflocculation? flocculation. deflocculation and flocculation. coagulation.
What are Floccules in pharmacy?
Formulating Stable Suspensions Flocculating agents are electrolytes which carry an electrical charge opposite that of the net zeta potential of the suspended particles. Floccules have approximately the same size particles; therefore a clear boundary is seen when the particles settle.
Which is more stable Flocculated or Deflocculated?
Most stable pharmaceutical suspensions are flocculated. In deflocculated suspension, individual particles are settling, so rate of sedimentation is slow which prevents entrapping of liquid medium which makes it difficult to re-disperse by agitation.
Is Vinegar a Deflocculant?
Vinegar is often used in ceramic slurries to change the viscosity (thicken it). While there are more effective flocculants (e.g. calcium chloride, epsom salts), vinegar is popular among potters simply because it is so available.
What are suspending agents?
: a substance (such as carrageenan, xanthan gum, or cellulose ether) that is added to fluids to promote particle suspension or dispersion and reduce sedimentation All these drinks can contain preservatives, and drinks other than juices can contain additives to colour, flavour and sweeten.
What are suspension differentiate Flocculated and Deflocculated suspension add a note on stability of suspension?
INTRODUCTION
| Flocculated suspension | Deflocculated suspension |
|---|---|
| Sediment is loosely packed and does not form a hard cake. | Sediment is tightly packed and forms a hard cake. |
| The supernatant is clear. | The supernatant is hazy. |
| Floccules stick to the sides of the bottle. | Particles do not stick to the sides of the bottle. |
Is Epsom salts a Deflocculant?
Epsom salts are my flocculant of choice. To use Epsom salts as a flocculant, the salts need to be dissolved in water. This breaks up the bond between the magnesium and the sulphate so the magnesium ions are free to attach themselves to the clay particles.
