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A flocculated suspension is a suspension in which particles of the suspension has undergone flocculation. Flocculation is the process in which colloids in a suspension can be obtained in an aggregated form.
What are the features of flocculated suspension?
Flocculated suspensions In this suspension type, the structure of the aggregates is quite rigid; hence they settle quickly to form a high sediment height and are easily redispersible because the particles constituting individual aggregates are sufficiently far apart from one another to preclude caking.
What is flocculated suspension in pharmacy?
In flocculated suspension the loose structure of the rapidly sedimenting flocs tends to preserve in the sediment, which contains an appreciable amount of entrapped liquid. The volume of final sediment is thus relatively large and is easily redispersed by agitation.
What is a suspension medicine?
A suspension is a liquid with small pieces of drug. The drug is not complete dissolved in the solution. Whenever you take a suspension, you should always shake (or stir) it so that you receive the right amount of drug every time you take it.
What suspension means?
A suspension is a heterogeneous mixture of a finely distributed solid in a liquid. The solid is not dissolved in the liquid, as is the case with a mixture of salt and water.
How many types of suspension are there in pharmacy?
Based on the route of administration, suspensions can be classified as oral, topical, ophthalmic, otic, or nasal suspensions. Each of these present unique challenges and requirements in terms of desired quality attributes. These are briefly described as follows: 1.
How do you make flocculated suspension?
Preparation of various types suspensions and determination of their sedimentation parameters
- Electrolyte and ionic surfactant can be used as flocculating agents to produce a flocculated suspension.
- The physical stability of the suspension is assist by determining the sedimentation volume or degree of flocculation.
How does a suspension appear?
An suspension is when you mix a liquid and a solid, where the solid does not dissolve in the liquid. If this appears then you have an suspension. The suspension will appear as small “grain” looking object floating in the solution.
What’s a coagulant?
Coagulants are a substance which cause particles in a liquid to curdle and clot together. Coagulation treatment chemicals are used in effluent water treatment processes for solids removal, water clarification, lime softening, sludge thickening, and solids dewatering.
What is stability of suspension?
Suspension stability can be theoretically estimated prior to the beginning of the formulating process based on the solid phase particle size, liquid phase density, and viscosity. In order to prevent formation of the solid sediment, controlled flocculation of the suspended bismuth subnitrate particles is recommended.
What are types of suspension in pharmacy?
- Based on General Classes. Oral suspension. Externally applied suspension.
- Based on Proportion of Solid Particles. Dilute suspension (2 to10%w/v solid) Concentrated suspension (50%w/v solid)
- Based on Electro Kinetic Nature of Solid. Particles. Flocculated suspension.
- Based on Size of Solid Particles.
What are 5 examples of suspension?
Examples of Suspension
- Muddy water.
- Milk of magnesia.
- Sand particles suspended in water.
- Flour in water.
- Slaked lime for whitewashing.
- Paints in which dyes are suspended in turpentine oil.
Why is flocculated suspension better?
There are suspensions that can be either flocculated or deflocculated. The main difference between flocculated and deflocculated suspension is that the rate of sedimentation in a flocculated suspension is rapid whereas the rate of sedimentation in a deflocculated suspension is slow.
What are 3 types of suspension?
There are three basic types of suspension components: linkages, springs, and shock absorbers.
What is flocculated and non flocculated suspension?
The suspension are said to be flocculated ,when the individual particles are in contact with each other and form a network like structure . Whereas in case of non-flocculated suspensions,the individual particles exists as a separate entity. In Non-flocculated suspensions The rate of sedimentation is slow.
What is suspension in your own words?
1 : the act of suspending : the state or period of being suspended: such as. a : temporary removal (as from office or privileges) b : temporary withholding (as of belief or decision) c : temporary abrogation of a law or rule.
How do coagulants work?
Coagulants work by creating a chemical reaction, eliminating negative charges that cause particles to repel each other. The action of these bubbles forces clots or flocs of particles to the water surface where they can be skimmed off. Dissolved air flotation is an alternative to sedimentation.
Is Redisperse difficult?
The repulsive forces between individual particles allow them to slip past each other as they sediment. The slow rate of settling prevents the entrapment of liquid within the sediment, which thus becomes compacted and can be very difficult to redisperse.
Is Flocculated a word?
verb (used without object), floc·cu·lat·ed, floc·cu·lat·ing. to form flocculent masses, as a cloud or a chemical precipitate; form aggregated or compound masses of particles.
What do you mean by Flocculated?
Flocculation, in the field of chemistry, is a process by which colloidal particles come out of suspension to sediment under the form of floc or flake, either spontaneously or due to the addition of a clarifying agent.
Why do Flocculated particles not cake?
Repulsive forces between particles are overcome and a hard cake is formed which is difficult, if not impossible, to redisperse. The sediment is loosely packed and possesses a scaffold-like structure (large volume of final sediment). Particles do not bond tightly to each other and a hard, dense cake does not form.
Why are suspending agents used?
2. SUSPENDING AGENTS Suspending agents also called thickening agents are used to stabilize suspensions are hydrophilic colloid i.e. substances that spontaneously form colloidal dispersions with water because of an affinity between the dispersed particles and the dispersion medium.
What are the advantages of suspension?
The following advantages can be obtained by formulating API as a suspension dosage form.
- Suspensions are a useful drug delivery system for therapeutic agents that have a low solubility.
- Pharmaceutical suspensions may be formulated to mask the unpleasant/ bitter taste of drug.
Which suspension is best?
The best front shock absorbers are the ones from the leaders in suspension.
- Bilstein B8 5100 Series Shock Absorbers.
- Skyjacker Hydro 7000 Shock Absorbers.
- Rancho RS9000XL Series Shock.
- Bilstein B6 Performance Shock Absorbers.
- Skyjacker Nitro 8000 Shock Absorbers.
- Eibach Pro-Truck Shocks.
- Fabtech FTS Shock Absorbers.
What is an ideal suspension?
An ideal suspension must possess the following properties:- 1 It should settle slowly and should be readily re-dispersed on gentle shaking of the container. 2 The particle size of the suspension remains fairly constant throughout its long period of undisturbed standing .
