Table of Contents
Definition. Flocculated Suspension: A flocculated suspension is a suspension in which particles have undergone flocculation. Deflocculated Suspension: A deflocculated suspension is a suspension where no flocculation has taken place.
What are the features of flocculated suspension?
Flocculated suspensions In this suspension type, the structure of the aggregates is quite rigid; hence they settle quickly to form a high sediment height and are easily redispersible because the particles constituting individual aggregates are sufficiently far apart from one another to preclude caking.
Which type of suspension is good Flocculated or Deflocculated?
INTRODUCTION
| Flocculated suspension | Deflocculated suspension |
|---|---|
| Sediment is loosely packed and does not form a hard cake. | Sediment is tightly packed and forms a hard cake. |
| The supernatant is clear. | The supernatant is hazy. |
| Floccules stick to the sides of the bottle. | Particles do not stick to the sides of the bottle. |
What is the best brand of 4×4 suspension?
One of their most popular products at the moment is the Dobinsons Monotube Suspension Kit which comes with the ability to adjust ride height in the front of the vehicle.Some of the common brands associated with suspension lift kits are:
- Dobinsons.
- Bilstein.
- Tough Dog.
- EFS.
- Fox.
How do you increase suspension stability?
There are some useful methods to improve the physical stability of a suspension, such as decreasing the salt concentration, addition of additives to regulate the osmolarity, as well as changes in excipient concentrations, unit operations in the process, origin and synthesis of the drug substance, polymorphic behavior
What is suspension flocculation?
Flocculation is a process whereby small particles in suspension are caused to aggregate, giving large clusters (flocs) that are much more easily separated than the original particles. The process is in widespread use in many industrial applications.
What is a suspension drug?
A suspension is a liquid with small pieces of drug. The drug is not complete dissolved in the solution. Whenever you take a suspension, you should always shake (or stir) it so that you receive the right amount of drug every time you take it.
How do you evaluate suspension?
Prepared suspension were evaluated by studying different parameters like pH, sedimentation volume, redispersibility, Flow rate (F), viscosity, degree of flocculation, effect of temperature etc.
What is flocculated and non flocculated suspension?
The suspension are said to be flocculated ,when the individual particles are in contact with each other and form a network like structure . Whereas in case of non-flocculated suspensions,the individual particles exists as a separate entity. In Non-flocculated suspensions The rate of sedimentation is slow.
What is stability of suspension?
Suspension stability can be theoretically estimated prior to the beginning of the formulating process based on the solid phase particle size, liquid phase density, and viscosity. In order to prevent formation of the solid sediment, controlled flocculation of the suspended bismuth subnitrate particles is recommended.
Which car has the smoothest suspension?
10 Cars with the Smoothest Ride
- Lincoln MKZ.
- Cadillac XTS.
- Buick LaCrosse.
- Mercedes-Benz S-Class.
- Audi A8 L.
- BMW 7 Series.
- Lexus LS.
- Genesis G90.
Why is flocculated suspension better?
There are suspensions that can be either flocculated or deflocculated. The main difference between flocculated and deflocculated suspension is that the rate of sedimentation in a flocculated suspension is rapid whereas the rate of sedimentation in a deflocculated suspension is slow.
How can you prevent suspension from sedimentation?
Slow down sedimentation by increasing viscosity of continuous phase. Velocity increases with the square of particle size making this the most critical parameter. For concentrated systems a crowding factor must be introduced which incorporates the phase volume Φ.
What is flocculated suspension in pharmacy?
In flocculated suspension the loose structure of the rapidly sedimenting flocs tends to preserve in the sediment, which contains an appreciable amount of entrapped liquid. The volume of final sediment is thus relatively large and is easily redispersed by agitation.
Why does flocculation occur in suspension?
Flocculation in the sulfamerazine suspension system is principally due to the chemical reaction that takes place between dioctyl sodium sulfosuccinate anions and the trivalent cations of the flocculating agent. Relatively strong bonding forces develop between the suspended particles, and floccules are formed.
How many types of suspension are there in pharmacy?
Based on the route of administration, suspensions can be classified as oral, topical, ophthalmic, otic, or nasal suspensions. Each of these present unique challenges and requirements in terms of desired quality attributes. These are briefly described as follows: 1.
Which suspension is more stable and why?
Suspension is more stable. This is because suspension does not mix with each other. The denser particles settle down at the bottom and makes the solution stable.
Which suspension is good for ride quality?
» Soft Suspension – Calling Suspension to be Soft Suspension means that the car has Taller Springs and thus is tuned for Comfort Oriented ride on slow speed, In Good City Roads – you will find the ride Plush, and when driven on marginal bad roads at slow speed – the overall ride turns to be soft.
How do you make flocculated suspension?
Preparation of various types suspensions and determination of their sedimentation parameters
- Electrolyte and ionic surfactant can be used as flocculating agents to produce a flocculated suspension.
- The physical stability of the suspension is assist by determining the sedimentation volume or degree of flocculation.
What does Flocculated mean?
The process by which individual particles of clay aggregate into clotlike masses or precipitate into small lumps. Flocculation occurs as a result of a chemical reaction between the clay particles and another substance, usually salt water.
What are types of suspension in pharmacy?
- Based on General Classes. Oral suspension. Externally applied suspension.
- Based on Proportion of Solid Particles. Dilute suspension (2 to10%w/v solid) Concentrated suspension (50%w/v solid)
- Based on Electro Kinetic Nature of Solid. Particles. Flocculated suspension.
- Based on Size of Solid Particles.
What are 3 types of suspension?
There are three basic types of suspension components: linkages, springs, and shock absorbers.
Is Redisperse difficult?
The repulsive forces between individual particles allow them to slip past each other as they sediment. The slow rate of settling prevents the entrapment of liquid within the sediment, which thus becomes compacted and can be very difficult to redisperse.
Which agents are used for stability of suspension?
Xanthan gum in drug delivery applications XG is widely used as a suspending agent and stabilizer in suspension due to its safety properties in food and drug applications. Moreover, it is soluble in water and can provide sufficient viscosity in low concentration.
Which suspension is best?
The best front shock absorbers are the ones from the leaders in suspension.
- Bilstein B8 5100 Series Shock Absorbers.
- Skyjacker Hydro 7000 Shock Absorbers.
- Rancho RS9000XL Series Shock.
- Bilstein B6 Performance Shock Absorbers.
- Skyjacker Nitro 8000 Shock Absorbers.
- Eibach Pro-Truck Shocks.
- Fabtech FTS Shock Absorbers.
