Table of Contents
Suspension is more stable. This is because suspension does not mix with each other. The denser particles settle down at the bottom and makes the solution stable.
Why is a suspension unstable while solutions are stable?
All suspensions, including coarse emulsions, are inherently thermodynamically unstable. They will, through random motion of the particles over time, aggregate because of the natural and dominant tendency to decrease the large specific surface area and excess surface energy.
Is suspension stable or unstable?
Suspensions are unstable from a thermodynamic point of view but can be kinetically stable over a longer period of time, which in turn can determine a suspension’s shelf life. This time span needs to be measured in order to provide accurate information to the consumer and ensure the best product quality.
Is a true solution stable?
True solutions are more stable than suspension. True solutions remain stable as the particles are almost uniform in size and do not settle down if left untouched for a given time interval.
How do you stabilize suspension?
Stabilizing a suspension There are various routes that can be undertaken to improve suspension stability – for example, stabilization can be achieved by: preventing coagulation through inter-particle repulsion. slowing down sedimentation by increasing the viscosity of the continuous phase.
What is Tyndall effect?
Tyndall effect, also called Tyndall phenomenon, scattering of a beam of light by a medium containing small suspended particles—e.g., smoke or dust in a room, which makes visible a light beam entering a window. The effect is named for the 19th-century British physicist John Tyndall, who first studied it extensively.
How do I know if my suspension is stable?
Suspension stability can be theoretically estimated prior to the beginning of the formulating process based on the solid phase particle size, liquid phase density, and viscosity. Stokes equation can be used to predict suspension stability in order to save time and resources.
What is used for increasing the stability of suspension?
There are some useful methods to improve the physical stability of a suspension, such as decreasing the salt concentration, addition of additives to regulate the osmolarity, as well as changes in excipient concentrations, unit operations in the process, origin and synthesis of the drug substance, polymorphic behavior
Why suspension is called unstable?
Suspensions are unstable from the thermodynamic point of view; however, they can be kinetically stable over a large period of time, which determines their shelf life.
Which is the most stable solution?
Suspension is more stable. This is because suspension does not mix with each other. The denser particles settle down at the bottom and makes the solution stable.
Why rheology is important for suspension stability?
Rheologic consideration is of great importance in the study of the stability of pharmaceutical suspensions. This is because the viscosity of a suspension can modify the sedimentation rate.
What is true solution stable?
Stability. Solution is stable as the solute particles do not settle down when left undisturbed. Stable.
What is the true solution?
A true solution is one that comprises all the particles in the correct composition and has been properly dissolved. As a result, a solution is known as a real solution. A true solution is a homogeneous mixture with consistent properties. Filtration cannot separate the solute from the solution in a true solution.
Which agent is used for stability of suspension?
Xanthan gum in drug delivery applications XG is widely used as a suspending agent and stabilizer in suspension due to its safety properties in food and drug applications. Moreover, it is soluble in water and can provide sufficient viscosity in low concentration.
What are the characteristics of true solution?
The characteristics of a true solution are: It is a homogeneous mixture of two or more substances . The solute parties cannot be seen with the naked eyes. It does not shoe tyndall effect. The solute particles if the solution cannot be separated by filtration . Size of true solution particles is less than 1nm.
What is the correct order of stability of solution?
I > IV > II > III.
Is a suspension stable?
It is important to understand that suspensions are kinetically stable, but thermodynamically unstable, system. Physical stability is defined as the condition in which the particles remain uniformly distributed throughout the dispersion without any signs of sedimentation.
Is suspension unstable solution?
A suspension is a heterogeneous mixture. The suspension is unstable. The particles of a suspension settle down after some time. A suspension scatters a beam of light passing through it because of its large particle size.
What are the stability problem of suspension?
Because suspensions are thermodynamically unstable system, physical stability of suspensions becomes as important as the chemical and biological stability. Physical stability of suspensions is the condition in which the particles do not aggregate and in which they remain uniformly distributed throughout the dispersion.
Can true solution be separated by filtration?
The components of a true solution (the solute and the solvent), cannot be separated by filtration. This is because both solute particles and the solvent molecules are very small as compared to the pores in the filter paper. But it can be separated using the process of distillation.
What are the properties of solution and suspension?
Difference between Suspension, Colloids and Solution Property Suspension Solution Visibility Dispersed particles are visible by naked eyes Dispersed phase particles are not visible by naked eyes Stability Unstable Stable Examples Flour and water mixture Sugar and water solution.
Which is more stable Fe2+ or Fe3+?
Fe3+ is more stable than Fe2+. In Fe3+ ions, there are five 3d half-filled orbitals and is more symmetrical than Fe2+. Whereas in Fe2+ ion there are four 3d half-filled orbitals and one orbital is filled.
What are 3 types of suspension?
There are three basic types of suspension components: linkages, springs, and shock absorbers.
Which is more stable true solution or colloid?
colloidal solution is the more stable true solution or suspension.
Is suspension stable class 9?
Suspensions are heterogeneous mixture of two or more substances. Particles of solute do not dissolve in solvent rather they remain suspended in bulk throughout. Therefore, suspension is not stable. The particles of suspension can be separated through the process of filtration.
